产品详情
产品名称FAK(Phospho-Tyr397) Antibody
来源种属Rabbit
克隆性Polyclonal
纯化Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
应用WB IHC
种属反应性Hu Ms Rt
特异性The antibody detects endogenous level of FAK only when phosphorylated at Tyrosine 397.
免疫原类型Peptide-KLH
免疫原描述Peptide sequence around phosphorylation site of tyrosine 397(D-D-Y(p)-A-E)derived from Human FAK.
基因/蛋白名称FAK
修饰Phospho
别名FAK; FAK1; PTK2
数据库入口号Swiss-Prot: Q05397
NCBI Protein: NP_001186578.1
浓度1.0mg/ml
配方Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
保存Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
应用详情
Predicted MW: 125kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50 - 1:100
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et al,Isobutyric acid promotes colorectal cancer metastasis through activating RACK1 In Cancer Sci On2023 OctbyJinglian Chen , Jiali Tang et al..PMID:37519194,
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et al,FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cellsIn PLoS OneOn2023 Apr 21byChunyan Xu? ,?Wenlu Zhang et al..PMID:37083591,
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